HitPredict

Interactor 1: SOCS1 (O15524)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Gene: SOCS1

Interactor 2: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 548
+	Hs
		411646 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Hs
		412092 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Hs
		181820 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		411833 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		412325 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		826580 VAV2_HUMAN (1-175): 2.65e-39: 144: 17.68		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		181819 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		411642 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		412086 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		181822 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		181793 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		454809 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		411639 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		412084 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		411647 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		411588 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		454808 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		412093 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		411996 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		454796 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPA_HUMAN (21-541): 0: 528: 29.89