HitPredict

Interactor 1: SOCS1 (O15524)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Gene: SOCS1

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 539
+	Hs
		411647 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		412093 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		454812 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		843146 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		181820 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		181819 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		826580 VAV2_HUMAN (1-175): 2.65e-39: 144: 17.68		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		411642 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		411833 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		412086 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		412325 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		454809 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		433290 YES_HUMAN (64-196): 8.58e-36: 133: 16.08		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		454845 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		411639 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		826606 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		412084 FYN_HUMAN (64-194): 1.54e-37: 138: 18.44		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		924818 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		454808 FGR_HUMAN (64-201): 3.97e-36: 134: 16.89		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		821158 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TCPE_HUMAN (13-535): 0: 540: 37.88