HitPredict

Interactor 1: MAFG (O15525)
Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF)
Gene: MAFG

Interactor 2: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 32296183, 32911434, 22942279, 23661758, 21988832, 24140708, 23737527, 25416956, 18692475, unassigned1304, 34591642
Identification Methods two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, mammalian protein protein interaction trap, two hybrid pooling approach, two hybrid prey pooling approach, two hybrid array, validated two hybrid, luminescence based mammalian interactome mapping, fluorescence correlation spectroscopy and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 4 others

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Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 162
Hs

1 605
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Last updated: 15 Jul 2024