Interactor 1: PDPK1 (O15530)
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
Gene: PDPK1

Interactor 2: PDPK1 (O15530)
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
Gene: PDPK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 25384981, 31980649, 10856237, 35271311, 11006271, 20562859
Identification Methods enzymatic study, affinity chromatography technology, in-gel kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH_3~PH_3, Pkinase~Pkinase
Common GO terms GO:0003323 - type B pancreatic cell development
GO:0004674 - protein serine/threonine kinase activity
GO:0004676 - 3-phosphoinositide-dependent protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 41 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 556
Hs

1 556
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Gm
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ Ce
+ At
+ At
+ Zm
+ Sp
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024