Interactor 1: PDPK1 (O15530)
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
Gene: PDPK1

Interactor 2: FGF2 (P09038)
Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2)
Gene: FGF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 31980649, 32707033, unassigned2173
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0043536 - positive regulation of blood vessel endothelial cell migration
GO:0045766 - positive regulation of angiogenesis
GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 556
Hs

1 288
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024