HitPredict

Interactor 1: PDPK1 (O15530)
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
Gene: PDPK1

Interactor 2: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 643
+	Hs
		182076 PDPK1_HUMAN (1-556): 0: 563: 100.00		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		564016 AKT1_HUMAN (46-410): 1.08e-141: 419: 31.35		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		503528 AKT1_HUMAN (46-410): 1.08e-141: 419: 31.35		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		503439 KAPCG_HUMAN (70-391): 1.4e-137: 404: 32.61		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		564041 KS6A3_HUMAN (4-354): 3.18e-103: 328: 24.20		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		503719 KS6A3_HUMAN (4-354): 3.18e-103: 328: 24.20		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Sc
		450168 PKH1_YEAST (80-361): 4.84e-80: 268: 46.28		HSP73_YEAST (8-643): 0: 910: 70.59
+	Sc
		450166 PKH3_YEAST (75-349): 7.67e-69: 240: 43.89		HSP73_YEAST (8-643): 0: 910: 70.59