Interactor 1: TPSN (O15533)
Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)
Gene: TAPBP

Interactor 2: TAP2 (Q03519)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)
Gene: TAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 12213826, 19201886
Identification Methods pull down, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0019885 - antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0030670 - phagocytic vesicle membrane
GO:0033116 - endoplasmic reticulum-Golgi intermediate compartment membrane
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 448
Hs

1 686
+ Rn
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024