HitPredict

Interactor 1: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Interactor 2: HCFC1 (P51610)
Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]
Gene: HCFC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0035097 - histone methyltransferase complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1401 Hs			1 2035
+	Hs
		183181 KDM6A_HUMAN (1-1401): 0: 1681: 100.00		HCFC2_HUMAN (1593-2009): 4.41e-38: 157: 32.51
+	Hs
		174733 OGT1_HUMAN (166-609): 5.45e-46: 183: 13.63		HCFC1_HUMAN (1-2035): 0: 643: 100.00
+	Hs
		175330 OGT1_HUMAN (166-609): 5.45e-46: 183: 13.63		HCFC2_HUMAN (1593-2009): 4.41e-38: 157: 32.51
+	Dm
		114494 M9PCJ7_DROME (176-524): 4.06e-42: 170: 42.55		HCF_DROME (948-2031): 9.87e-34: 144: 15.87