HitPredict

Interactor 1: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	34269483, 17713478
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1401 Hs			1 136
+	Hs
		183122 KDM6A_HUMAN (1-1401): 0: 1681: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		183127 KDM6A_HUMAN (1-1401): 0: 1681: 100.00		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		174804 OGT1_HUMAN (166-609): 5.45e-46: 183: 13.63		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Mm
		952745 KDM6B_MOUSE (336-979): 3.39e-20: 100: 16.72		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Hs
		934895 CTR9_HUMAN (173-542): 2.86e-18: 93.5: 10.97		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		935352 CDC23_HUMAN (134-642): 8.91e-16: 84.6: 11.21		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		165840 KDM6B_HUMAN (252-941): 3.78e-14: 80.1: 16.69		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		672808 CDC27_HUMAN (96-315): 2.28e-11: 70.6: 22.75		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		672810 CDC27_HUMAN (96-315): 2.28e-11: 70.6: 22.75		H33_HUMAN (1-136): 2.73e-61: 186: 96.32