HitPredict

Interactor 1: CLD3 (O15551)
Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1)
Gene: CLDN3

Interactor 2: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0016020 - membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 220 Hs			1 189
+	Hs
		183184 CLD3_HUMAN (1-220): 1.59e-86: 256: 100.00		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		325483 CLD1_HUMAN (2-205): 7.28e-78: 234: 49.27		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		325493 CLD1_HUMAN (2-205): 7.28e-78: 234: 49.27		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		325484 CLD1_HUMAN (2-205): 7.28e-78: 234: 49.27		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00