Interactor 1: MEFV (O15553)
Pyrin (Marenostrin)
Gene: MEFV

Interactor 2: MEFV (O15553)
Pyrin (Marenostrin)
Gene: MEFV

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 25006247, 17964261, 22829933
Identification Methods pull down, cross-linking study, molecular sieving, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~PRY, PRY~SPRY, PYRIN~PYRIN, SPRY~SPRY, zf-B_box~zf-B_box
Common GO terms GO:0001726 - ruffle
GO:0002221 - pattern recognition receptor signaling pathway
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 28 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 781
Hs

1 781
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024