Interactor 1: MEFV (O15553)
Pyrin (Marenostrin)
Gene: MEFV
Interactor 2: NALP2 (Q9NX02)
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)
Gene: NLRP2
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17431422 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PYRIN~PYRIN |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0032731 - positive regulation of interleukin-1 beta production GO:0045087 - innate immune response |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
