HitPredict

Interactor 1: STIP1 (O16259)
Stress-induced-phosphoprotein 1 (CeSTI1) (STI1) (Hsc70/Hsp90-organizing protein) (CeHop) (Hop)
Gene: sti-1

Interactor 2: HSP90 (Q18688)
Heat shock protein 90 (Abnormal dauer formation protein 21)
Gene: daf-21

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.678

The method score is based on:

Property Details
Experiments 19467242, 19559711, 25988162
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0008340 - determination of adult lifespan
GO:0009408 - response to heat
GO:0022417 - protein maturation by protein folding
GO:0101031 - protein folding chaperone complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 320
Ce

1 702
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm
+ At
+ Sp
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024