Interactor 1: ORC1 (O16810)
Origin recognition complex subunit 1 (DmORC1)
Gene: ORC1

Interactor 2: ORC2 (Q24168)
Origin recognition complex subunit 2 (DmORC2)
Gene: ORC2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 12490953, 25762138, 29899147, 32848132, 24137536, 16188887
Identification Methods affinity chromatography technology, x-ray crystallography, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~ORC2, Cdc6_C~ORC2
Common GO terms GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005664 - nuclear origin of replication recognition complex
GO:0006270 - DNA replication initiation
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 924
Dm

1 618
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp
+ Sp
+ At
+ Sc
+ Sc
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024