Interactor 1: ORC1 (O16810)
Origin recognition complex subunit 1 (DmORC1)
Gene: ORC1

Interactor 2: Q9W102 (Q9W102)
Origin recognition complex subunit 4
Gene: Orc4

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 24137536, 29899147, 25762138, 32848132
Identification Methods affinity chromatography technology, pull down, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~ORC4_C, AAA~AAA_lid_10, AAA_lid_10~ORC4_C, AAA~Cdc6_C, Cdc6_C~ORC4_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005664 - nuclear origin of replication recognition complex
GO:0006270 - DNA replication initiation
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 924
Dm

1 459
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Sp
+ Sp
+ Sp
+ Sp
+ Sc
+ Sc
+ Sc
+ Sp

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Last updated: 15 Jul 2024