Interactor 1: COS (O16844)
Kinesin-like protein costa (Kinesin-like protein costal2)
Gene: COS

Interactor 2: CI (P19538)
Transcriptional activator cubitus interruptus (Transcriptional activator ci) (ci form of 155 kDa) (ci-155) (ci full-length protein) (ciFL) [Cleaved into: Transcriptional repressor cubitus interruptus (Transcriptional repressor ci) (ci C-terminally truncated form) (ci form of 75 kDa) (ci-75)]
Gene: CI

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 9244298, 10825151, 15063184, 20850429, 21852395, 26120032, 26271100, 22306085, 14636583, 14523402, 9244297, 11090136, 14645371, 11914126, 17881487, 15710747, unassigned4
Identification Methods affinity chromatography technology, pull down, two hybrid, biochemical, anti tag coimmunoprecipitation, fluorescence microscopy, two hybrid fragment pooling approach, experimental interaction detection
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0007224 - smoothened signaling pathway
GO:0019901 - protein kinase binding
GO:0035301 - Hedgehog signaling complex
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1201
Dm

1 1397
+ Dm
+ Dr
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024