Interactor 1: COS (O16844)
Kinesin-like protein costa (Kinesin-like protein costal2)
Gene: COS

Interactor 2: FUSED (P23647)
Serine/threonine-protein kinase fused (EC 2.7.11.1)
Gene: fu

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 10825151, 11495917, 9244297, 21852395, 25289679, 21844892, 22306085, 14645371, 30541874, 31279575, 15710747, 11839821, 14636583, 14523402, 14614827, 18987629, 26271100, 15063184, 25633354, 17881487 and 4 others

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Identification Methods pull down, affinity chromatography technology, enzymatic study, protein complementation assay, two hybrid, anti bait coimmunoprecipitation, two hybrid fragment pooling approach, experimental interaction detection
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005119 - smoothened binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005929 - cilium
GO:0007224 - smoothened signaling pathway
and 3 others

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Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1201
Dm

1 805
+ Dm
+ Dm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024