Interactor 1: FOXO (O16850)
Forkhead box protein O (FOXO) (Abnormal dauer formation protein 16)
Gene: daf-16

Interactor 2: AKT1 (Q17941)
Serine/threonine-protein kinase akt-1 (EC 2.7.11.1) (Protein kinase B akt-1) (PKB akt-1)
Gene: akt-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.666

The method score is based on:

Property Details
Experiments 18358814, 15068796
Identification Methods enzymatic study, affinity chromatography technology, pull down, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008286 - insulin receptor signaling pathway
GO:0008340 - determination of adult lifespan
GO:0008582 - regulation of synaptic assembly at neuromuscular junction
and 3 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 541
Ce

1 541
+ Ce
+ Hs
+ Rn
+ Dm
+ Mm
+ Hs
+ Hs
+ Dm
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024