HitPredict

Interactor 1: PRS10 (O17071)
Probable 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit rpt-4) (Proteasome regulatory particle ATPase-like protein 4)
Gene: rpt-4

Interactor 2: PRS6A (O76371)
26S protease regulatory subunit 6A (Proteasome regulatory particle ATPase-like protein 5)
Gene: rpt-5

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 12679813, 14704431, 18692475, 19123269, 26952210, 11559592, unassigned701
Identification Methods two hybrid, affinity chromatography technology, two hybrid pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB~Prot_ATP_ID_OB
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
GO:0036402 - proteasome-activating activity
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 406
Ce

1 430
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024