HitPredict

Interactor 1: NFYC1 (O17072)
Nuclear transcription factor Y subunit nfyc-1 (CAAT box DNA-binding protein subunit nfyc-1)
Gene: nfyc-1

Interactor 2: NFYB1 (O17286)
Nuclear transcription factor Y subunit nfyb-1 (CAAT box DNA-binding protein subunit nfyb-1)
Gene: nfyb-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.833

The method score is based on:

Property Details
Experiments 23791784, 17574230, 11731503
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 232
Ce

1 403
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024