HitPredict

Interactor 1: O17144 (O17144)
Cyclin-H
Gene: CycH

Interactor 2: CDK1 (P23572)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15575970
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_C_2~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 325 Dm			1 297
+	Hs
		625350 CCNA1_HUMAN (19-290): 3.71e-85: 265: 13.46		CDK2_HUMAN (1-293): 7.76e-161: 450: 62.80
+	Mm
		956329 CCNA1_MOUSE (15-290): 9.41e-84: 260: 12.55		CDK2_MOUSE (1-293): 8.94e-152: 430: 53.67
+	Mm
		851183 CCNA2_MOUSE (1-288): 5.91e-80: 251: 14.09		CDK2_MOUSE (1-293): 8.94e-152: 430: 53.67
+	Hs
		414855 CCNA1_HUMAN (19-290): 3.71e-85: 265: 13.46		CDK1_HUMAN (1-292): 1.95e-146: 414: 72.95
+	Hs
		236679 CCNT1_HUMAN (21-319): 3.31e-77: 251: 14.56		CDK1_HUMAN (1-292): 1.95e-146: 414: 72.95
+	At
		621661 CCB12_ARATH (15-287): 6.82e-83: 259: 14.60		CDKA1_ARATH (1-290): 3.16e-143: 406: 63.23
+	At
		621697 CCA31_ARATH (15-289): 2.76e-83: 257: 12.95		CDKA1_ARATH (1-290): 3.16e-143: 406: 63.23
+	Mm
		509476 CCNA2_MOUSE (1-288): 5.91e-80: 251: 14.09		CDK1_MOUSE (1-292): 4.41e-145: 411: 72.60
+	At
		621691 CCA24_ARATH (15-289): 2.73e-79: 250: 12.95		CDKA1_ARATH (1-290): 3.16e-143: 406: 63.23
+	At
		1103350 CCB12_ARATH (15-287): 6.82e-83: 259: 14.60		CKB12_ARATH (1-294): 1.56e-132: 380: 50.80
+	At
		1106926 CCB13_ARATH (15-287): 5.22e-84: 261: 14.96		CDKD2_ARATH (1-294): 5.72e-131: 377: 42.18
+	At
		1103369 CCA31_ARATH (15-289): 2.76e-83: 257: 12.95		CKB12_ARATH (1-294): 1.56e-132: 380: 50.80
+	At
		1106906 CCB12_ARATH (15-287): 6.82e-83: 259: 14.60		CKB21_ARATH (1-295): 1.75e-131: 377: 48.19
+	At
		1106907 CCB12_ARATH (15-287): 6.82e-83: 259: 14.60		CKB22_ARATH (1-295): 1.69e-130: 375: 50.50
+	At
		1227954 CCA31_ARATH (15-289): 2.76e-83: 257: 12.95		CKB21_ARATH (1-295): 1.75e-131: 377: 48.19
+	At
		1103366 CCA24_ARATH (15-289): 2.73e-79: 250: 12.95		CKB12_ARATH (1-294): 1.56e-132: 380: 50.80
+	At
		639340 CCB12_ARATH (15-287): 6.82e-83: 259: 14.60		CKB11_ARATH (1-294): 3.46e-129: 371: 50.49
+	At
		639364 CCA31_ARATH (15-289): 2.76e-83: 257: 12.95		CKB11_ARATH (1-294): 3.46e-129: 371: 50.49
+	At
		1227952 CCA24_ARATH (15-289): 2.73e-79: 250: 12.95		CKB21_ARATH (1-295): 1.75e-131: 377: 48.19
+	At
		639358 CCA24_ARATH (15-289): 2.73e-79: 250: 12.95		CKB11_ARATH (1-294): 3.46e-129: 371: 50.49