HitPredict

Interactor 1: O17311 (O17311)
Proteasome subunit beta
Gene: Prosbeta2

Interactor 2: PSA2 (P40301)
Proteasome subunit alpha type-2 (PROS-Dm25) (Proteasome 25 kDa subunit)
Gene: Prosalpha2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pr_beta_C~Proteasome, Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0000502 - proteasome complex GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Dm			1 234
+	Dm
		1278650 Q9VUJ1_DROME (1-272): 1.77e-98: 290: 98.16		PSA5_DROME (1-233): 1.55e-97: 286: 30.71
+	Dm
		771324 Q9VUJ1_DROME (1-272): 1.77e-98: 290: 98.16		PSA2_DROME (1-234): 2.1e-95: 280: 100.00
+	Sp
		293714 PSA3_SCHPO (3-245): 4.38e-83: 251: 12.85		PSA2_SCHPO (3-233): 1.96e-107: 311: 58.20
+	Hs
		656296 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38
+	Hs
		656164 PSB10_HUMAN (10-270): 5.71e-89: 267: 50.38		PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38
+	Hs
		637732 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11
+	Hs
		637640 PSB10_HUMAN (10-270): 5.71e-89: 267: 50.38		PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11
+	Hs
		637527 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSA1_HUMAN (1-233): 5.72e-92: 272: 30.67
+	Hs
		637346 PSB10_HUMAN (10-270): 5.71e-89: 267: 50.38		PSA1_HUMAN (1-233): 5.72e-92: 272: 30.67
+	Hs
		893733 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSA6_HUMAN (3-233): 6.35e-91: 269: 32.49
+	Hs
		156341 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSA7_HUMAN (6-231): 9.41e-91: 268: 36.52
+	Sc
		625917 PSB2_YEAST (15-272): 5.58e-84: 253: 53.08		PSA5_YEAST (1-233): 3.17e-91: 270: 31.12
+	Sc
		619405 PSB2_YEAST (15-272): 5.58e-84: 253: 53.08		PSA2_YEAST (3-216): 2.64e-81: 245: 59.91
+	Dm
		611671 Q9VUJ1_DROME (1-272): 1.77e-98: 290: 98.16		PSA71_DROME (3-230): 2.89e-44: 150: 36.48
+	Hs
		1250771 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSMA8_HUMAN (5-216): 1.1e-47: 159: 40.27
+	Sp
		1000000 PSB2_SCHPO (13-271): 3.89e-88: 264: 52.51		PSA4_SCHPO (6-214): 2.76e-48: 161: 37.92
+	Sc
		619325 PSB2_YEAST (15-272): 5.58e-84: 253: 53.08		PSA3_YEAST (1-230): 7.06e-50: 165: 39.75
+	Hs
		638179 PSB7_HUMAN (1-268): 1.86e-89: 268: 62.55		PSA4_HUMAN (3-217): 3.05e-44: 150: 39.64
+	Sp
		1013784 PSA5_SCHPO (1-238): 8.72e-84: 252: 20.40		PSA4_SCHPO (6-214): 2.76e-48: 161: 37.92
+	Sc
		625941 PSB2_YEAST (15-272): 5.58e-84: 253: 53.08		PSA4_YEAST (6-212): 6.3e-44: 149: 40.28