HitPredict

Interactor 1: RAN (O17915)
GTP-binding nuclear protein ran-1 (Ras-related nuclear protein 1)
Gene: ran-1

Interactor 2: VAB1 (O61460)
Ephrin receptor 1 (EC 2.7.10.1) (Tyrosine-protein kinase Eph receptor) (Variable abnormal protein 1)
Gene: vab-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	18472420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0009792 - embryo development ending in birth or egg hatching
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Ce			1 1122
+	Hs
		665466 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		EPHA8_HUMAN (31-1101): 0: 964: 28.04
+	Hs
		665604 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		EPHB2_HUMAN (31-1099): 0: 832: 21.43
+	Hs
		1070202 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		EPHA7_HUMAN (15-1097): 0: 825: 21.82
+	Hs
		665398 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		EPHA3_HUMAN (27-1102): 0: 825: 21.83
+	Hs
		665456 RAB7A_HUMAN (10-168): 1.56e-28: 108: 33.13		EPHA8_HUMAN (31-1101): 0: 964: 28.04
+	Hs
		665242 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		EPHA2_HUMAN (30-1081): 0: 779: 22.60
+	Hs
		665197 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		EPHA2_HUMAN (30-1081): 0: 779: 22.60
+	Hs
		872534 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		EPHB4_HUMAN (17-1108): 0: 756: 22.29
+	Hs
		665174 RAB7A_HUMAN (10-168): 1.56e-28: 108: 33.13		EPHA2_HUMAN (30-1081): 0: 779: 22.60
+	Hs
		435598 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		IGF1R_HUMAN (323-1082): 3.42e-133: 440: 18.03
+	Hs
		507936 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		FGFR1_HUMAN (412-1057): 4.17e-134: 429: 19.85
+	Hs
		508023 RB11B_HUMAN (3-204): 3.52e-77: 232: 25.94		FGFR1_HUMAN (412-1057): 4.17e-134: 429: 19.85
+	Hs
		507934 RAB8A_HUMAN (1-196): 2.93e-76: 230: 25.50		FGFR1_HUMAN (412-1057): 4.17e-134: 429: 19.85
+	Hs
		507935 RAB14_HUMAN (2-202): 3.31e-76: 230: 25.00		FGFR1_HUMAN (412-1057): 4.17e-134: 429: 19.85
+	Hs
		987290 RAB1B_HUMAN (4-194): 1.28e-78: 235: 27.32		TYRO3_HUMAN (319-1037): 2.85e-126: 410: 19.21
+	Hs
		507916 RAB7A_HUMAN (10-168): 1.56e-28: 108: 33.13		FGFR1_HUMAN (412-1057): 4.17e-134: 429: 19.85
+	Hs
		433769 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		LYN_HUMAN (685-987): 2.02e-51: 191: 38.03
+	Hs
		522882 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		SRC_HUMAN (745-1000): 6.89e-50: 187: 42.02
+	Hs
		412121 RAN_HUMAN (1-215): 7.12e-76: 229: 86.57		FYN_HUMAN (685-1000): 2.77e-51: 191: 36.28
+	Hs
		523004 RB11B_HUMAN (3-204): 3.52e-77: 232: 25.94		SRC_HUMAN (745-1000): 6.89e-50: 187: 42.02