HitPredict

Interactor 1: RAN (O17915)
GTP-binding nuclear protein ran-1 (Ras-related nuclear protein 1)
Gene: ran-1

Interactor 2: CDC42 (Q05062)
Cell division control protein 42 homolog (CDC42Ce)
Gene: cdc-42

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	26780296, unassigned1274
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Ce			1 191
+	Hs
		1070394 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RHOJ_HUMAN (2-189): 5.52e-84: 248: 63.30
+	Hs
		564470 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RHOQ_HUMAN (4-187): 3.27e-91: 266: 67.94
+	Hs
		925294 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Hs
		894031 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39
+	Hs
		545392 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71
+	Hs
		900494 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87
+	Hs
		918948 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RHOJ_HUMAN (2-189): 5.52e-84: 248: 63.30
+	Hs
		892386 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RAC3_HUMAN (1-177): 5.96e-76: 227: 70.62
+	Hs
		918847 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Hs
		913995 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Hs
		918849 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RHOG_HUMAN (1-191): 5.85e-79: 235: 58.12
+	Hs
		893872 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39
+	Hs
		545307 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71
+	Zm
		73944 B4FAE1_MAIZE (4-205): 6.63e-83: 246: 26.83		B4FAE1_MAIZE (4-188): 5.1e-74: 223: 23.12
+	Hs
		900355 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87
+	Hs
		893868 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39
+	Hs
		545305 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71
+	Hs
		436244 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RHOC_HUMAN (5-191): 1.01e-75: 227: 50.80
+	Hs
		892305 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAC3_HUMAN (1-177): 5.96e-76: 227: 70.62
+	Hs
		918896 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RHOU_HUMAN (4-187): 1.21e-72: 221: 58.82