HitPredict

Interactor 1: BLM (O18017)
RecQ-like DNA helicase blm-1 (EC 5.6.2.4) (Bloom syndrome protein homolog) (DNA 3'-5' helicase BLM) (High incidence of males protein 6) (RecQ helicase homolog)
Gene: him-6

Interactor 2: ATR (Q22258)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (ATM-like protein 1) (Ataxia telangiectasia and Rad3-related protein homolog) (ATR homolog) (Ce-atl-1)
Gene: atl-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 11778048, 12679813, 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000723 - telomere maintenance
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 988
Ce

1 2531
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024