HitPredict

Interactor 1: BLM (O18017)
RecQ-like DNA helicase blm-1 (EC 5.6.2.4) (Bloom syndrome protein homolog) (DNA 3'-5' helicase BLM) (High incidence of males protein 6) (RecQ helicase homolog)
Gene: him-6

Interactor 2: TOP2 (Q23670)
DNA topoisomerase 2 top-2 (EC 5.6.2.2) (DNA topoisomerase II)
Gene: top-2

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 12679813, 11778048, 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Toprim
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005694 - chromosome
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 988
Ce

1 1520
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024