HitPredict

Interactor 1: MAB3 (O18214)
Protein male abnormal 3
Gene: mab-3

Interactor 2: HMX (Q18533)
Homeobox protein mls-2 (Mesodermal lineage specification protein 2)
Gene: mls-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 290 Ce			1 341
+	Ce
		185261 MAB3_CAEEL (1-290): 5.71e-123: 354: 100.00		HM43_CAEEL (116-322): 7.72e-38: 137: 25.00
+	Ce
		106220 MAB3_CAEEL (1-290): 5.71e-123: 354: 100.00		VAB3_CAEEL (171-337): 1.04e-32: 128: 25.15
+	Ce
		1090148 Q9TXN8_CAEEL (26-89): 2.53e-09: 59.5: 32.81		HMX_CAEEL (1-341): 1.05e-65: 212: 100.00
+	Dm
		950053 Q9VDF1_DROME (61-148): 2.29e-28: 112: 37.50		UBX_DROME (69-262): 4.82e-30: 119: 16.67
+	Dm
		221150 DSX_DROME (69-163): 3.46e-22: 98: 27.37		HTH_DROME (6-326): 1.36e-31: 125: 16.23
+	Ce
		1090009 Q9TXN8_CAEEL (26-89): 2.53e-09: 59.5: 32.81		HM43_CAEEL (116-322): 7.72e-38: 137: 25.00
+	Ce
		106284 Q9TXN8_CAEEL (26-89): 2.53e-09: 59.5: 32.81		VAB3_CAEEL (171-337): 1.04e-32: 128: 25.15
+	Ce
		712519 Q9TXN8_CAEEL (26-89): 2.53e-09: 59.5: 32.81		LIN39_CAEEL (71-285): 9.85e-30: 115: 21.40