HitPredict

Interactor 1: O18683 (O18683)
LD42724p (Phosphatidylinositol 3-kinase regulatory subunit) (p60 protein)
Gene: Pi3K21B

Interactor 2: Q8IPG1 (Q8IPG1)
PDGF- and VEGF-receptor related, isoform B (EC 2.7.10.1) (PDGF- and VEGF-receptor related, isoform D) (PDGF- and VEGF-receptor related, isoform L)
Gene: Pvr

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	22068330
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 506 Dm			1 1509
+	Dm
		112209 ABL_DROME (6-425): 3.71e-96: 320: 14.12		M9MRE1_DROME (19-1509): 0: 1009: 99.40
+	Dm
		112231 SRC42_DROME (308-500): 1.02e-33: 135: 21.46		M9MRE1_DROME (19-1509): 0: 1009: 99.40
+	Hs
		738170 ABL2_HUMAN (12-506): 3.28e-99: 325: 13.02		FLT3_HUMAN (212-1306): 1e-140: 460: 18.08
+	Hs
		337376 ABL1_HUMAN (12-499): 2.29e-93: 308: 12.33		FLT3_HUMAN (212-1306): 1e-140: 460: 18.08
+	Hs
		411619 LCK_HUMAN (215-500): 2.47e-35: 140: 16.72		FLT3_HUMAN (212-1306): 1e-140: 460: 18.08
+	Hs
		607907 ABL2_HUMAN (12-506): 3.28e-99: 325: 13.02		FGFR4_HUMAN (44-234): 1.26e-21: 103: 12.21
+	Hs
		452370 ABL2_HUMAN (12-506): 3.28e-99: 325: 13.02		PGFRB_HUMAN (1-470): 1.82e-18: 94.3: 14.09
+	Hs
		499244 ABL2_HUMAN (12-506): 3.28e-99: 325: 13.02		KIT_HUMAN (28-407): 2.14e-15: 84.3: 8.74
+	Hs
		337317 ABL1_HUMAN (12-499): 2.29e-93: 308: 12.33		PGFRB_HUMAN (1-470): 1.82e-18: 94.3: 14.09
+	Hs
		507897 ABL2_HUMAN (12-506): 3.28e-99: 325: 13.02		FGFR1_HUMAN (18-149): 2.94e-11: 70.4: 9.80
+	Hs
		337322 ABL1_HUMAN (12-499): 2.29e-93: 308: 12.33		KIT_HUMAN (28-407): 2.14e-15: 84.3: 8.74
+	Hs
		729640 SHC2_HUMAN (3-128): 5.38e-45: 168: 30.95		VGFR2_HUMAN (8-485): 5.21e-41: 167: 12.02
+	Hs
		572619 SHC2_HUMAN (3-128): 5.38e-45: 168: 30.95		VGFR1_HUMAN (1-145): 7.38e-21: 102: 14.38
+	Hs
		499256 SHC2_HUMAN (3-128): 5.38e-45: 168: 30.95		KIT_HUMAN (28-407): 2.14e-15: 84.3: 8.74
+	Hs
		452364 SHC1_HUMAN (5-128): 3.54e-33: 134: 28.23		PGFRB_HUMAN (1-470): 1.82e-18: 94.3: 14.09
+	Hs
		499279 SHC3_HUMAN (9-130): 2.43e-35: 141: 29.51		KIT_HUMAN (28-407): 2.14e-15: 84.3: 8.74
+	Hs
		411567 LCK_HUMAN (215-500): 2.47e-35: 140: 16.72		KIT_HUMAN (28-407): 2.14e-15: 84.3: 8.74
+	Hs
		426989 SHC1_HUMAN (5-128): 3.54e-33: 134: 28.23		CSF1R_HUMAN (2-407): 9.23e-17: 88.5: 9.30
+	Hs
		499237 SHC1_HUMAN (5-128): 3.54e-33: 134: 28.23		KIT_HUMAN (28-407): 2.14e-15: 84.3: 8.74
+	Hs
		434141 SHC1_HUMAN (5-128): 3.54e-33: 134: 28.23		RET_HUMAN (859-968): 3.5e-14: 80.1: 40.91