HitPredict

Interactor 1: BRI1 (O22476)
Protein BRASSINOSTEROID INSENSITIVE 1 (AtBRI1) (EC 2.7.10.1) (EC 2.7.11.1) (Brassinosteroid LRR receptor kinase)
Gene: BRI1

Interactor 2: SERK1 (Q94AG2)
Somatic embryogenesis receptor kinase 1 (AtSERK1) (EC 2.7.10.1) (EC 2.7.11.1) (Somatic embryogenesis receptor-like kinase 1)
Gene: SERK1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.900

The method score is based on:

Property Details
Experiments 23929946, 19105183, 16473966
Identification Methods x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfer, molecular sieving, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, blue native page
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Island~LRR_1, Island~LRRNT_2, LRR_1~LRR_1, LRR_1~LRRNT_2, LRR_1~LRR_8, LRR_8~LRRNT_2, LRR_8~PK_Tyr_Ser-Thr, LRRNT_2~LRRNT_2, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0009742 - brassinosteroid mediated signaling pathway
GO:0032991 - protein-containing complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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1 625
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024