HitPredict

Interactor 1: MSI4 (O22607)
WD-40 repeat-containing protein MSI4 (Altered cold-responsive gene 1 protein) (Nucleosome remodeling factor complex component 4) (Protein MULTICOPY SUPPRESSOR OF IRA1 4) (AtMSI4)
Gene: MSI4

Interactor 2: HDA6 (Q9FML2)
Histone deacetylase 6 (AtHDA6) (EC 3.5.1.98)
Gene: HDA6

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.657

Property	Details
Experiments	22102827, 24220632
Identification Methods	pull down, affinity chromatography technology, protein complementation assay, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0048510 - regulation of timing of transition from vegetative to reproductive phase
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 507 At			1 471
+	At
		187010 MSI4_ARATH (1-507): 9.05e-125: 375: 100.00		HDA9_ARATH (17-433): 0: 558: 54.12
+	Hs
		903202 WDR5_HUMAN (4-365): 7.42e-51: 178: 10.48		HDAC1_HUMAN (13-449): 0: 624: 57.30
+	Hs
		903404 WDR5_HUMAN (4-365): 7.42e-51: 178: 10.48		HDAC2_HUMAN (16-470): 0: 620: 57.27
+	At
		187011 MSI4_ARATH (1-507): 9.05e-125: 375: 100.00		HDA5_ARATH (1-415): 4.5e-139: 416: 22.78
+	Hs
		245600 TBL1X_HUMAN (53-369): 6.87e-39: 151: 11.38		HDAC1_HUMAN (13-449): 0: 624: 57.30
+	Hs
		245623 TBL1X_HUMAN (53-369): 6.87e-39: 151: 11.38		HDAC2_HUMAN (16-470): 0: 620: 57.27
+	Mm
		140271 RBBP4_MOUSE (291-507): 3.94e-33: 132: 20.35		HDAC1_MOUSE (13-449): 0: 627: 57.98
+	Hs
		997711 RBBP4_HUMAN (291-507): 3.94e-33: 132: 20.35		HDAC1_HUMAN (13-449): 0: 624: 57.30
+	Hs
		997836 RBBP4_HUMAN (291-507): 3.94e-33: 132: 20.35		HDAC2_HUMAN (16-470): 0: 620: 57.27
+	Dm
		1182201 EBI_DROME (145-507): 2.75e-57: 204: 16.98		Q7KTS4_DROME (17-433): 0: 541: 52.78
+	Dm
		1279322 EBI_DROME (145-507): 2.75e-57: 204: 16.98		Q9VNC2_DROME (17-433): 0: 537: 52.55
+	Hs
		177249 WDR5_HUMAN (4-365): 7.42e-51: 178: 10.48		HDAC3_HUMAN (19-436): 0: 559: 55.77
+	At
		186874 MSI1_ARATH (291-507): 8.67e-34: 134: 17.33		HDA19_ARATH (4-462): 0: 578: 59.87
+	Hs
		177148 TBL1X_HUMAN (53-369): 6.87e-39: 151: 11.38		HDAC3_HUMAN (19-436): 0: 559: 55.77
+	Ce
		184840 LIN53_CAEEL (291-507): 5.11e-34: 134: 20.44		HDA1_CAEEL (7-459): 0: 576: 54.96
+	Hs
		177278 RBBP4_HUMAN (291-507): 3.94e-33: 132: 20.35		HDAC3_HUMAN (19-436): 0: 559: 55.77
+	Hs
		177377 TBL1R_HUMAN (60-324): 8.02e-32: 130: 13.78		HDAC3_HUMAN (19-436): 0: 559: 55.77
+	Dm
		1212080 EBI_DROME (145-507): 2.75e-57: 204: 16.98		Q8I9J6_DROME (11-442): 6.76e-137: 426: 20.44
+	At
		187009 MSI4_ARATH (1-507): 9.05e-125: 375: 100.00		HDA15_ARATH (152-341): 2.49e-24: 107: 31.80
+	Hs
		997941 RBBP4_HUMAN (291-507): 3.94e-33: 132: 20.35		HDAC6_HUMAN (22-337): 1.34e-89: 298: 22.56