HitPredict

Interactor 1: AP2M (O23140)
AP-2 complex subunit mu (Adaptor protein complex AP-2 subunit mu) (Adaptor protein-2 mu-adaptin) (Adaptor-related protein complex 2 subunit mu) (At-muA-Ad) (Clathrin assembly protein complex 2 mu medium chain) (Mu2-adaptin) (Protein AP47/50) (AtAP47/50)
Gene: AP2M

Interactor 2: AP2S (Q84WL9)
AP-2 complex subunit sigma (Adaptor AP-2 17 kDa protein) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Sigma2-adaptin)
Gene: AP17

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23975897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adap_comp_sub~Clat_adaptor_s
Common GO terms	GO:0030122 - AP-2 adaptor complex GO:0035615 - clathrin adaptor activity GO:0072583 - clathrin-dependent endocytosis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 438 At			1 142
+	Hs
		880428 AP1M1_HUMAN (3-437): 5.74e-179: 508: 44.73		AP1S2_HUMAN (2-142): 1.87e-53: 167: 48.94
+	Hs
		1299170 AP1M1_HUMAN (3-437): 5.74e-179: 508: 44.73		AP1S3_HUMAN (1-142): 1.19e-50: 159: 46.48
+	Hs
		903697 AP1M2_HUMAN (3-437): 1.25e-171: 489: 40.83		AP1S1_HUMAN (1-142): 2.97e-54: 169: 45.78
+	Hs
		880436 AP1M2_HUMAN (3-437): 1.25e-171: 489: 40.83		AP1S2_HUMAN (2-142): 1.87e-53: 167: 48.94
+	Hs
		1315736 AP1M1_HUMAN (3-437): 5.74e-179: 508: 44.73		AP1M2_HUMAN (2-142): 4.47e-41: 143: 17.36
+	Hs
		1299174 AP1M2_HUMAN (3-437): 1.25e-171: 489: 40.83		AP1S3_HUMAN (1-142): 1.19e-50: 159: 46.48
+	Hs
		903691 AP2M1_HUMAN (7-438): 8.12e-165: 472: 47.49		AP1S1_HUMAN (1-142): 2.97e-54: 169: 45.78
+	Hs
		880423 AP2M1_HUMAN (7-438): 8.12e-165: 472: 47.49		AP1S2_HUMAN (2-142): 1.87e-53: 167: 48.94
+	Hs
		1287472 AP2M1_HUMAN (7-438): 8.12e-165: 472: 47.49		AP1S3_HUMAN (1-142): 1.19e-50: 159: 46.48
+	Hs
		864097 AP2M1_HUMAN (7-438): 8.12e-165: 472: 47.49		AP2S1_HUMAN (1-142): 8.08e-46: 147: 61.27
+	Mm
		915560 AP2M1_MOUSE (7-438): 8.12e-165: 472: 47.49		AP2S1_MOUSE (1-142): 8.08e-46: 147: 61.27
+	Dm
		248304 O62530_DROME (7-438): 1.06e-160: 462: 46.83		Q9VDC3_DROME (1-142): 7.41e-46: 147: 59.86
+	Sc
		715577 AP1M1_YEAST (5-437): 1.16e-149: 435: 37.76		AP1S1_YEAST (2-142): 4.04e-44: 143: 41.26
+	Hs
		1267501 AP3M1_HUMAN (7-437): 1.75e-129: 382: 25.29		AP3S1_HUMAN (1-142): 1.28e-53: 168: 41.22
+	Hs
		887150 AP3M1_HUMAN (7-437): 1.75e-129: 382: 25.29		AP3S2_HUMAN (1-142): 3.93e-51: 162: 39.19
+	Hs
		864052 AP3M2_HUMAN (7-437): 6.5e-123: 365: 25.06		AP3S1_HUMAN (1-142): 1.28e-53: 168: 41.22
+	Hs
		864041 AP3M2_HUMAN (7-437): 6.5e-123: 365: 25.06		AP3S2_HUMAN (1-142): 3.93e-51: 162: 39.19
+	Hs
		119741 AP4M1_HUMAN (5-437): 7.24e-123: 366: 26.80		AP4S1_HUMAN (1-141): 1.04e-42: 139: 43.97
+	Sc
		959833 AP2M_YEAST (5-437): 6.78e-122: 365: 29.68		AP2S_YEAST (2-142): 1.05e-39: 132: 48.97