HitPredict

Interactor 1: CKS1 (O23249)
Cyclin-dependent kinases regulatory subunit 1 (CKS1-At)
Gene: CKS1

Interactor 2: CCA34 (Q3ECW2)
Cyclin-A3-4 (G2/mitotic-specific cyclin-A3-4) (CycA3;4)
Gene: CYCA3-4

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.647

Property	Details
Experiments	20407024, 20706207, 17426018
Identification Methods	protein complementation assay, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 87 At			1 370
+	At
		1108315 CKS2_ARATH (1-80): 7.09e-43: 135: 90.00		CCA34_ARATH (1-370): 9.15e-135: 390: 100.00
+	At
		1324477 CKS2_ARATH (1-80): 7.09e-43: 135: 90.00		CCA31_ARATH (3-366): 1.67e-119: 351: 66.03
+	At
		188148 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCA23_ARATH (6-361): 7.64e-107: 322: 40.78
+	At
		48925 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCA33_ARATH (43-364): 1.25e-107: 320: 63.04
+	At
		48953 CKS2_ARATH (1-80): 7.09e-43: 135: 90.00		CCA33_ARATH (43-364): 1.25e-107: 320: 63.04
+	At
		188178 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCB24_ARATH (5-358): 5.43e-97: 296: 28.53
+	At
		188149 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCB12_ARATH (3-358): 1.78e-96: 295: 29.12
+	At
		188167 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCB23_ARATH (2-356): 1.43e-95: 293: 27.84
+	At
		1352139 CKS2_ARATH (1-80): 7.09e-43: 135: 90.00		CCB24_ARATH (5-358): 5.43e-97: 296: 28.53
+	At
		1106919 CKS2_ARATH (1-80): 7.09e-43: 135: 90.00		CCB12_ARATH (3-358): 1.78e-96: 295: 29.12
+	At
		188134 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCB14_ARATH (7-359): 2.14e-92: 283: 28.93
+	Hs
		895411 CKS1_HUMAN (3-77): 1.31e-35: 117: 64.00		CCNA1_HUMAN (15-359): 3.17e-101: 308: 35.84
+	Hs
		538505 CKS1_HUMAN (3-77): 1.31e-35: 117: 64.00		CCNB1_HUMAN (39-365): 1.05e-98: 301: 32.83
+	Hs
		303840 CKS1_HUMAN (3-77): 1.31e-35: 117: 64.00		CCNB2_HUMAN (4-365): 1.88e-98: 299: 28.88
+	Hs
		590156 CKS1_HUMAN (3-77): 1.31e-35: 117: 64.00		CCNA2_HUMAN (1-358): 2.23e-97: 297: 33.61
+	Dm
		593450 Q9VHN1_DROME (2-71): 2.35e-37: 122: 70.00		CCNB_DROME (8-349): 2.96e-85: 269: 27.07
+	Dm
		1336979 Q9VHN1_DROME (2-71): 2.35e-37: 122: 70.00		CCNB3_DROME (5-362): 4.18e-80: 257: 27.99
+	Dm
		540500 Q9VHN1_DROME (2-71): 2.35e-37: 122: 70.00		CCNA_DROME (95-350): 7.57e-54: 186: 43.80
+	At
		188150 CKS1_ARATH (1-87): 6.02e-46: 143: 100.00		CCB22_ARATH (117-349): 8.96e-38: 142: 39.91
+	At
		1106940 CKS2_ARATH (1-80): 7.09e-43: 135: 90.00		CCB22_ARATH (117-349): 8.96e-38: 142: 39.91