HitPredict

Interactor 1: O24886 (O24886)
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase)
Gene: fcl

Interactor 2: O24886 (O24886)
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase)
Gene: fcl

Species: Helicobacter pylori 26695

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.53	1.00	0.730

Property	Details
Experiments	11196647, 24627523
Identification Methods	two hybrid, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Epimerase~Epimerase
Common GO terms	GO:0016853 - isomerase activity GO:0042351 - 'de novo' GDP-L-fucose biosynthetic process GO:0050577 - GDP-L-fucose synthase activity GO:0070401 - NADP+ binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 310 Hp			1 310
+	At
		1352607 UGE5_ARATH (1-308): 4.68e-94: 284: 16.57		UGE2_ARATH (1-308): 5.45e-94: 284: 17.15
+	At
		1115052 UGE2_ARATH (1-308): 5.45e-94: 284: 17.15		UGE1_ARATH (1-308): 7.16e-92: 278: 15.90
+	Ec
		448030 GALE_ECOLI (3-309): 1.91e-92: 279: 18.88		GALE_ECOLI (3-309): 1.91e-92: 279: 18.88
+	At
		1115051 UGE1_ARATH (1-308): 7.16e-92: 278: 15.90		UGE1_ARATH (1-308): 7.16e-92: 278: 15.90
+	Ec
		685475 FCL_ECOLI (1-309): 1.11e-90: 274: 36.16		FCL_ECOLI (1-309): 1.11e-90: 274: 36.16
+	Hs
		1053477 GALE_HUMAN (1-308): 5.08e-90: 273: 17.63		GALE_HUMAN (1-308): 5.08e-90: 273: 17.63
+	Dm
		1376196 GALE_DROME (4-309): 2.62e-85: 261: 15.03		GALE_DROME (4-309): 2.62e-85: 261: 15.03
+	Cj
		1004695 Q0P8I6_CAMJE (2-307): 1.14e-84: 260: 29.07		Q0P8I6_CAMJE (2-307): 1.14e-84: 260: 29.07
+	Sc
		381667 GAL10_YEAST (2-308): 7.54e-78: 252: 17.53		GAL10_YEAST (2-308): 7.54e-78: 252: 17.53
+	Cj
		1005707 Q0P8T8_CAMJE (3-309): 3.64e-78: 242: 20.24		Q0P8T8_CAMJE (3-309): 3.64e-78: 242: 20.24
+	Hs
		1044322 FCL_HUMAN (2-309): 1.16e-75: 236: 25.88		FCL_HUMAN (2-309): 1.16e-75: 236: 25.88
+	Cj
		1007101 Q0P9C3_CAMJE (3-306): 4.99e-75: 234: 20.12		Q0P9C3_CAMJE (3-306): 4.99e-75: 234: 20.12
+	Dm
		1376345 FCL_DROME (3-309): 2.01e-74: 232: 27.22		FCL_DROME (3-309): 2.01e-74: 232: 27.22
+	At
		1353053 RHM1_ARATH (2-300): 3.2e-24: 104: 15.14		RHM1_ARATH (2-300): 3.2e-24: 104: 15.14
+	Ec
		741812 RMLB1_ECOLI (4-305): 5.39e-23: 99: 18.50		RMLB1_ECOLI (4-305): 5.39e-23: 99: 18.50