Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: RPA49 (Q9GZS1)
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
Gene: POLR1E

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.90 0.874

The method score is based on:

Property Details
Experiments 15226435, 34079125, 24981860, 35271311, 31839598
Identification Methods pull down, proximity labelling technology, far western blotting, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_polI_A34~RNA_pol_I_A49
Common GO terms GO:0001650 - fibrillar center
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005736 - RNA polymerase I complex
GO:0006361 - transcription initiation at RNA polymerase I promoter
Homologous interactions 0

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Last updated: 11Aug2025