Interactor 1: M3K5 (O35099)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: Map3k5
Interactor 2: M3K6 (Q9WTR2)
Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)
Gene: Map3k6
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17210579 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ASK_PH~MAP3K_TRAF_bd, Pkinase~Pkinase |
| Common GO terms | GO:0004709 - MAP kinase kinase kinase activity GO:0005524 - ATP binding GO:0016310 - phosphorylation GO:0106310 - protein serine kinase activity |
| Homologous interactions | 18 |
Homologous interactions
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Last updated: 15 Jul 2024
