HitPredict

Interactor 1: PHB2 (O35129)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity)
Gene: PHB2

Interactor 2: RAB4B (Q91ZR1)
Ras-related protein Rab-4B (EC 3.6.5.2)
Gene: RAB4B

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26885862
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 299 Mm			1 213
+	Hs
		591992 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85
+	Hs
		895239 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Hs
		914308 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29
+	Mm
		931071 PHB1_MOUSE (22-280): 6.64e-86: 260: 51.54		RAB4B_MOUSE (1-213): 1.89e-89: 263: 100.00
+	Hs
		591752 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85
+	Hs
		718677 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Hs
		646159 STOM_HUMAN (1-286): 2.42e-84: 256: 17.93		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Hs
		718708 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29
+	Dm
		185571 Q9VWL0_DROME (3-284): 2.12e-75: 236: 19.23		RAB2_DROME (4-211): 4.79e-85: 252: 51.42
+	Hs
		73286 B4E2V5_HUMAN (38-282): 3.72e-65: 206: 20.48		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Dm
		185672 Q0E924_DROME (24-298): 7.77e-90: 271: 71.64		O18335_DROME (3-208): 1.12e-56: 180: 47.09