Interactor 1: SMAD7 (O35253)
Mothers against decapentaplegic homolog 7 (MAD homolog 7) (Mothers against DPP homolog 7) (Mothers against decapentaplegic homolog 8) (MAD homolog 8) (Mothers against DPP homolog 8) (SMAD family member 7) (SMAD 7) (Smad7)
Gene: SMAD7

Interactor 2: SMAD3 (Q8BUN5)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)
Gene: SMAD3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 30315770
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MH1~MH1, MH2~MH2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001657 - ureteric bud development
GO:0005518 - collagen binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 12 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 426
Mm

1 425
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
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+ Mm
+ Dm
+ Dm

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Last updated: 15 Jul 2024