HitPredict

Interactor 1: NEB2 (O35274)
Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)
Gene: Ppp1r9b

Interactor 2: KCC2D (P15791)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: Camk2d

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20124353
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004672 - protein kinase activity GO:0005737 - cytoplasm GO:0043025 - neuronal cell body GO:0044325 - transmembrane transporter binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Rn			1 533
+	Mm
		1161534 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2D_MOUSE (1-533): 0: 614: 92.68
+	Mm
		659460 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2B_MOUSE (1-512): 0: 576: 77.31
+	Rn
		192509 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		KCC2B_RAT (1-512): 0: 572: 77.12
+	Mm
		1164026 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2G_MOUSE (1-512): 0: 571: 81.29
+	Rn
		192511 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		KCC2G_RAT (1-512): 0: 567: 78.94
+	Rn
		192510 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		KCC2A_RAT (1-511): 0: 551: 80.82
+	Mm
		515240 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2A_MOUSE (1-511): 0: 551: 80.82
+	Mm
		1143346 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		KCC2D_MOUSE (1-533): 0: 614: 92.68
+	Mm
		1131547 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		Q5SVI3_MOUSE (1-512): 0: 580: 82.05
+	Mm
		659457 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		KCC2B_MOUSE (1-512): 0: 576: 77.31
+	Mm
		515234 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		KCC2A_MOUSE (1-511): 0: 551: 80.82
+	Rn
		506715 LRRC7_RAT (5-586): 1.44e-40: 164: 15.11		KCC2A_RAT (1-511): 0: 551: 80.82
+	Hs
		1021591 DLG1_HUMAN (43-803): 4.57e-35: 145: 10.10		KCC2A_HUMAN (1-511): 0: 551: 80.82
+	Rn
		506740 DLG1_RAT (43-697): 2.37e-31: 133: 10.54		KCC2A_RAT (1-511): 0: 551: 80.82
+	Hs
		159190 DLG4_HUMAN (332-780): 1.01e-51: 195: 14.76		CSKP_HUMAN (10-308): 9.6e-88: 291: 47.71
+	Hs
		159255 ERBIN_HUMAN (14-583): 2.28e-42: 169: 13.46		CSKP_HUMAN (10-308): 9.6e-88: 291: 47.71
+	Hs
		159200 DLG1_HUMAN (43-803): 4.57e-35: 145: 10.10		CSKP_HUMAN (10-308): 9.6e-88: 291: 47.71
+	Mm
		251104 DLG1_MOUSE (43-727): 7.64e-34: 141: 9.99		CSKP_MOUSE (10-308): 9.6e-88: 291: 47.71
+	Rn
		1144009 DLG1_RAT (43-697): 2.37e-31: 133: 10.54		CSKP_RAT (10-308): 7.24e-88: 291: 47.71
+	Hs
		108908 H0YKB7_HUMAN (277-650): 2.27e-42: 162: 16.88		KCC1A_HUMAN (12-307): 2.83e-70: 231: 43.10