HitPredict

Interactor 1: TNR11 (O35305)
Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265)
Gene: Tnfrsf11a

Interactor 2: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.681

The method score is based on:

Property Details
Experiments 11406619, 14500659, 16184196, 10097072
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001503 - ossification
GO:0005829 - cytosol
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0045672 - positive regulation of osteoclast differentiation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 625
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1 530
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024