HitPredict

Interactor 1: SRSF5 (O35326)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: TRA2B (P62996)
Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (Silica-induced gene 41 protein) (SIG-41) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)
Gene: TRA2B

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 269 Mm			1 288
+	Hs
		992758 SRSF1_HUMAN (2-173): 1.02e-57: 186: 42.94		TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06
+	Hs
		925011 SRSF1_HUMAN (2-173): 1.02e-57: 186: 42.94		TRA2B_HUMAN (1-267): 9.15e-34: 126: 100.00
+	Hs
		1028541 SRSF9_HUMAN (2-219): 1.07e-52: 172: 32.74		TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06
+	Mm
		925167 SRSF9_MOUSE (2-219): 1.35e-54: 177: 34.08		TRA2B_MOUSE (1-267): 9.15e-34: 126: 100.00
+	Hs
		993707 SRSF4_HUMAN (5-268): 1.26e-49: 172: 53.79		TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06
+	Hs
		1028644 SRSF5_HUMAN (1-179): 1.44e-51: 171: 100.00		TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06
+	Hs
		925012 SRSF4_HUMAN (5-268): 1.26e-49: 172: 53.79		TRA2B_HUMAN (1-267): 9.15e-34: 126: 100.00
+	Hs
		925020 SRSF9_HUMAN (2-219): 1.07e-52: 172: 32.74		TRA2B_HUMAN (1-267): 9.15e-34: 126: 100.00
+	Dm
		580160 SRR55_DROME (1-179): 6.4e-56: 185: 58.64		TRA2_DROME (102-267): 2.45e-25: 103: 44.58
+	Hs
		992743 SRSF1_HUMAN (2-173): 1.02e-57: 186: 42.94		ELAV2_HUMAN (52-244): 6.85e-24: 101: 20.00
+	Dm
		580166 Q9V3W7_DROME (2-190): 2e-55: 180: 37.31		TRA2_DROME (102-267): 2.45e-25: 103: 44.58
+	Hs
		516478 SRSF1_HUMAN (2-173): 1.02e-57: 186: 42.94		PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99
+	Hs
		1028634 SRSF9_HUMAN (2-219): 1.07e-52: 172: 32.74		PPIE_HUMAN (118-201): 7.87e-27: 107: 36.91
+	Hs
		993869 SRSF4_HUMAN (5-268): 1.26e-49: 172: 53.79		PPIE_HUMAN (118-201): 7.87e-27: 107: 36.91
+	Hs
		992769 SRSF1_HUMAN (2-173): 1.02e-57: 186: 42.94		RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83
+	Mm
		936481 SRSF1_MOUSE (2-173): 1.02e-57: 186: 42.94		TIAR_MOUSE (112-270): 5.86e-18: 84.8: 17.77
+	Mm
		857340 SRSF1_MOUSE (2-173): 1.02e-57: 186: 42.94		TIA1_MOUSE (113-248): 1.05e-17: 84.1: 18.42
+	Hs
		516493 SRSF9_HUMAN (2-219): 1.07e-52: 172: 32.74		PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99
+	Hs
		1028546 SRSF9_HUMAN (2-219): 1.07e-52: 172: 32.74		RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83
+	Hs
		993716 SRSF4_HUMAN (5-268): 1.26e-49: 172: 53.79		RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83