HitPredict

Interactor 1: IMA4 (O35344)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3)
Gene: Kpna3

Interactor 2: CHD8 (Q09XV5)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Axis duplication inhibitor) (Duplin)
Gene: CHD8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	11744694
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 521 Mm			1 2582
+	Hs
		134969 IMA3_HUMAN (1-521): 1e-157: 461: 85.99		CHD8_HUMAN (1-2582): 0: 2363: 95.67
+	Mm
		853539 IMA1_MOUSE (1-521): 5.66e-133: 397: 48.31		CHD8_MOUSE (1-2582): 0: 2401: 100.00
+	Hs
		238743 IMA7_HUMAN (4-520): 1.58e-134: 402: 46.81		CHD8_HUMAN (1-2582): 0: 2363: 95.67
+	Hs
		853480 IMA1_HUMAN (3-521): 2.59e-134: 401: 48.49		CHD8_HUMAN (1-2582): 0: 2363: 95.67
+	Hs
		168673 IMA6_HUMAN (4-520): 1.37e-131: 394: 47.10		CHD8_HUMAN (1-2582): 0: 2363: 95.67
+	Hs
		131423 IMA4_HUMAN (1-521): 2.21e-158: 462: 99.23		CHD3_HUMAN (399-2065): 0: 1009: 23.47
+	Hs
		853257 IMA1_HUMAN (3-521): 2.59e-134: 401: 48.49		CHD3_HUMAN (399-2065): 0: 1009: 23.47
+	Hs
		853580 IMA5_HUMAN (5-520): 1.58e-128: 386: 45.71		CHD3_HUMAN (399-2065): 0: 1009: 23.47
+	Dm
		283986 O76522_DROME (6-521): 6.64e-137: 407: 67.70		CHDM_DROME (411-2065): 0: 893: 22.24
+	Hs
		229344 IMA5_HUMAN (5-520): 1.58e-128: 386: 45.71		SMCA5_HUMAN (689-1724): 0: 873: 26.72
+	Hs
		131405 IMA4_HUMAN (1-521): 2.21e-158: 462: 99.23		SMCA4_HUMAN (69-1480): 0: 788: 23.06
+	Hs
		658643 IMA5_HUMAN (5-520): 1.58e-128: 386: 45.71		SMCA1_HUMAN (654-1705): 0: 858: 26.04
+	Zm
		11289 A0A1D6FC42_MAIZE (1-521): 4.65e-147: 434: 42.51		A0A1D6IBX9_MAIZE (534-1453): 0: 807: 33.76
+	Zm
		12493 A0A1D6FMC0_MAIZE (1-521): 4.8e-143: 425: 39.62		A0A1D6IBX9_MAIZE (534-1453): 0: 807: 33.76
+	Hs
		846901 IMA1_HUMAN (3-521): 2.59e-134: 401: 48.49		SMCA4_HUMAN (69-1480): 0: 788: 23.06
+	Hs
		846902 IMA5_HUMAN (5-520): 1.58e-128: 386: 45.71		SMCA4_HUMAN (69-1480): 0: 788: 23.06
+	Hs
		134899 IMA3_HUMAN (1-521): 1e-157: 461: 85.99		CHD4_HUMAN (1416-2065): 7.18e-39: 162: 10.48
+	Hs
		238679 IMA7_HUMAN (4-520): 1.58e-134: 402: 46.81		CHD4_HUMAN (1416-2065): 7.18e-39: 162: 10.48
+	Hs
		853286 IMA1_HUMAN (3-521): 2.59e-134: 401: 48.49		CHD4_HUMAN (1416-2065): 7.18e-39: 162: 10.48
+	Hs
		168636 IMA6_HUMAN (4-520): 1.37e-131: 394: 47.10		CHD4_HUMAN (1416-2065): 7.18e-39: 162: 10.48