Interactor 1: CAN1 (O35350)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Micromolar-calpain) (muCANP)
Gene: Capn1

Interactor 2: KCC2A (P11798)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: Camk2a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 24725413
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_8~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0010666 - positive regulation of cardiac muscle cell apoptotic process
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 713
Mm

1 478
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs
+ Dm
+ Hs
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024