HitPredict

Interactor 1: APBA1 (O35430)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Interactor 2: KCJ12 (P52188)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: Kcnj12

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15024025
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Rn			1 427
+	Hs
		970700 APBA1_HUMAN (1-839): 0: 915: 93.14		KCJ12_HUMAN (1-427): 0: 741: 96.07
+	Hs
		132819 SDCB1_HUMAN (549-836): 1.64e-76: 252: 19.52		KCNJ2_HUMAN (6-427): 0: 699: 70.82
+	Rn
		677769 DLG4_RAT (386-761): 4.64e-33: 138: 14.60		KCJ12_RAT (1-427): 0: 747: 100.00
+	Hs
		942342 DLG4_HUMAN (386-761): 5.54e-33: 138: 14.60		KCJ12_HUMAN (1-427): 0: 741: 96.07
+	Rn
		852397 DLG1_RAT (425-825): 6.04e-29: 126: 14.32		KCJ12_RAT (1-427): 0: 747: 100.00
+	Hs
		1021490 DLG1_HUMAN (361-825): 1.79e-30: 131: 14.58		KCJ12_HUMAN (1-427): 0: 741: 96.07
+	Rn
		852400 DLG2_RAT (355-737): 4.38e-26: 117: 13.67		KCJ12_RAT (1-427): 0: 747: 100.00
+	Hs
		80982 DLG1_HUMAN (361-825): 1.79e-30: 131: 14.58		KCJ18_HUMAN (1-427): 0: 732: 94.69
+	Hs
		929762 DLG4_HUMAN (386-761): 5.54e-33: 138: 14.60		KCNJ2_HUMAN (6-427): 0: 699: 70.82
+	Hs
		929764 DLG1_HUMAN (361-825): 1.79e-30: 131: 14.58		KCNJ2_HUMAN (6-427): 0: 699: 70.82
+	Rn
		1144015 DLG1_RAT (425-825): 6.04e-29: 126: 14.32		KCNJ2_RAT (6-427): 0: 695: 70.82
+	Mm
		852403 DLG4_MOUSE (386-761): 7.76e-33: 138: 14.39		KCNJ4_MOUSE (32-427): 0: 574: 62.73
+	Hs
		816146 DLG4_HUMAN (386-761): 5.54e-33: 138: 14.60		KCNJ4_HUMAN (31-427): 0: 571: 62.81
+	Hs
		816147 DLG1_HUMAN (361-825): 1.79e-30: 131: 14.58		KCNJ4_HUMAN (31-427): 0: 571: 62.81
+	Mm
		1143540 DLG4_MOUSE (386-761): 7.76e-33: 138: 14.39		Q9QYK8_MOUSE (39-386): 0: 562: 70.38
+	Hs
		816159 DLG1_HUMAN (361-825): 1.79e-30: 131: 14.58		KCNJ6_HUMAN (40-381): 0: 527: 52.92
+	Mm
		291382 DLG4_MOUSE (386-761): 7.76e-33: 138: 14.39		KCNJ1_MOUSE (39-358): 1.39e-172: 489: 49.85
+	Mm
		1265183 LNX2_MOUSE (516-833): 9.99e-40: 159: 14.05		KCJ10_MOUSE (43-354): 1.24e-159: 456: 44.59
+	Mm
		1143568 DLG4_MOUSE (386-761): 7.76e-33: 138: 14.39		KCJ16_MOUSE (36-363): 5.94e-164: 469: 49.09
+	Mm
		1143532 DLG4_MOUSE (386-761): 7.76e-33: 138: 14.39		KCJ10_MOUSE (43-354): 1.24e-159: 456: 44.59