Interactor 1: NOTC2 (O35516)
Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]
Gene: Notch2

Interactor 2: SUH (P31266)
Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa)
Gene: Rbpj

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11518718
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~BTD, Ank_2~LAG1-DNAbind, Ank_2~TIG_SUH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001947 - heart looping
GO:0002437 - inflammatory response to antigenic stimulus
GO:0005634 - nucleus
and 9 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 2473
Mm

1 526
+ Hs
+ Hs
+ Dm
+ Mm
+ Mm
+ Dm
+ Mm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024