Interactor 1: NOTC2 (O35516)
Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]
Gene: Notch2

Interactor 2: DLK1 (Q09163)
Protein delta homolog 1 (DLK-1) (Adipocyte differentiation inhibitor protein) (Preadipocyte factor 1) (Pref-1) [Cleaved into: Fetal antigen 1 (FA1)]
Gene: DLK1

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10958687
Identification Methods coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, EGF~EGF_CA
Common GO terms GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0035264 - multicellular organism growth
GO:0045672 - positive regulation of osteoclast differentiation
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 2473
Mm

1 385
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024