HitPredict

Interactor 1: STX1A (O35526)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Interactor 2: VAMP2 (P63044)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 20114047, 18385322, 21151134, 16269331, 26290230, 20798282, 26437117, 26280336
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Synaptobrevin, Synaptobrevin~Syntaxin
Common GO terms GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005886 - plasma membrane
GO:0008021 - synaptic vesicle
GO:0008076 - voltage-gated potassium channel complex
and 18 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 288
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1 116
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024