HitPredict

Interactor 1: DAXX (O35613)
Death domain-associated protein 6 (Daxx)
Gene: DAXX

Interactor 2: TIF1B (Q62318)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-A-interacting protein) (KRIP-1) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: Trim28

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.594

The method score is based on:

Property Details
Experiments 29084956, 25938714
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000792 - heterochromatin
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
and 1 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 739
Mm

1 834
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024