Interactor 1: AXIN1 (O35625)
Axin-1 (Axis inhibition protein 1) (Protein Fused)
Gene: AXIN1

Interactor 2: Q8BNP7 (Q8BNP7)
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein
Gene: Apc

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 18316368, 15327768
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Axin_b-cat_bind
Common GO terms GO:0008013 - beta-catenin binding
GO:0016055 - Wnt signaling pathway
GO:0030877 - beta-catenin destruction complex
GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 863
Mm

1 1056
+ Hs
+ Rn
+ Xl
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024