HitPredict

Interactor 1: SOCS1 (O35716)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)
Gene: SOCS1

Interactor 2: PHAG1 (Q3U1F9)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	16920712
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	GO:0035556 - intracellular signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 212 Mm			1 429
+	Mm
		223013 NCK2_MOUSE (2-176): 5.1e-42: 147: 18.64		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		1112224 NCK1_MOUSE (4-175): 9.1e-41: 144: 17.82		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		763390 FYN_MOUSE (69-195): 3.04e-36: 134: 18.98		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		643088 P85A_MOUSE (76-181): 2.34e-17: 81.7: 23.59		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Hs
		789135 FRK_HUMAN (69-195): 8.38e-38: 138: 20.46		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		412375 FYN_HUMAN (69-195): 3.04e-36: 134: 18.98		PHAG1_HUMAN (1-429): 0: 705: 78.21