HitPredict

Interactor 1: HNRH1 (O35737)
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene: Hnrnph1

Interactor 2: FUS (P56959)
RNA-binding protein FUS (Protein pigpen)
Gene: FUS

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32325033
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0043484 - regulation of RNA splicing
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 449 Mm			1 518
+	Hs
		1031411 PABP4_HUMAN (1-447): 1.08e-83: 271: 14.56		RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41
+	Hs
		516620 PABP1_HUMAN (1-446): 8.23e-83: 269: 14.35		RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41
+	Hs
		726795 PABP4_HUMAN (1-447): 1.08e-83: 271: 14.56		FUS_HUMAN (1-518): 1.02e-35: 141: 84.82
+	Hs
		516383 PABP1_HUMAN (1-446): 8.23e-83: 269: 14.35		FUS_HUMAN (1-518): 1.02e-35: 141: 84.82
+	Hs
		682916 HNRH1_HUMAN (1-449): 1.29e-75: 245: 99.78		RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41
+	Hs
		682708 HNRH1_HUMAN (1-449): 1.29e-75: 245: 99.78		FUS_HUMAN (1-518): 1.02e-35: 141: 84.82
+	Hs
		682776 HNRH1_HUMAN (1-449): 1.29e-75: 245: 99.78		EWS_HUMAN (3-444): 5.23e-30: 126: 34.13
+	Hs
		1031507 PABP4_HUMAN (1-447): 1.08e-83: 271: 14.56		RBM8A_HUMAN (238-359): 1.45e-23: 99.2: 29.51
+	Hs
		516768 PABP1_HUMAN (1-446): 8.23e-83: 269: 14.35		RBM8A_HUMAN (238-359): 1.45e-23: 99.2: 29.51
+	Hs
		516495 PABP4_HUMAN (1-447): 1.08e-83: 271: 14.56		PABP1_HUMAN (269-372): 1.46e-11: 69: 21.15
+	Hs
		516339 PABP1_HUMAN (1-446): 8.23e-83: 269: 14.35		PABP1_HUMAN (269-372): 1.46e-11: 69: 21.15
+	Hs
		516689 PABP1_HUMAN (1-446): 8.23e-83: 269: 14.35		PABP3_HUMAN (269-372): 4.42e-10: 64.3: 19.23
+	Hs
		682823 HNRH1_HUMAN (1-449): 1.29e-75: 245: 99.78		SF3B4_HUMAN (258-386): 1.96e-17: 86.5: 20.14
+	Hs
		474021 PAB4L_HUMAN (3-188): 1.15e-38: 145: 15.03		PABP4_HUMAN (274-372): 4.92e-13: 73.6: 22.22
+	Dm
		1249158 Q9VBQ1_DROME (101-223): 8.97e-18: 88: 15.45		Q8SYC0_DROME (104-369): 7.75e-33: 130: 13.76
+	Hs
		642763 ELAV4_HUMAN (104-193): 4.38e-16: 81.4: 15.39		EWS_HUMAN (3-444): 5.23e-30: 126: 34.13
+	Hs
		123885 HNRPF_HUMAN (253-438): 9.84e-12: 68.4: 24.47		SPT5H_HUMAN (15-228): 1.41e-31: 131: 15.81
+	Dm
		1213098 Q8IMS8_DROME (101-223): 6.66e-18: 88.3: 15.45		Q8IP90_DROME (270-371): 6.91e-12: 70.1: 22.86